FGF2 Protein (AA 10-155)
Our Local Distributor
北京 101111
Quick Overview for FGF2 Protein (AA 10-155) (ABIN2017858)
抗原
See all FGF2 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
产品特性
- AA 10-155
-
产品特性
- ED50 < 1.0 ng/mL, measured by a cell proliferation assay using 3T3 cells, corresponding to a specific activity of > 1 x 10^6 units/mg.
-
内毒素水平
- < 0.2 EU/μg, determined by LAL method.
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
-
缓冲液
- Lyophilized after extensive dialysis against PBS.
-
储存条件
- -80 °C
-
储存方法
- Lyophilized recombinant bovine Fibroblast Growth Factor-basic (rbFGF-basic) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rbFGF-basic remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
-
有效期
- 6 months
-
-
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
-
别名
- Fibroblast Growth Factor-Basic (FGF-Basic)
-
背景
-
Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. Like other FGF family members, FGF-basic has the beta trefoil structure. In vivo, FGF-basic is produced by a variety of cells, including cardiomycotes, fibroblasts, and vascular cells. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling. The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury.Recombinant bovine Fibroblast Growth Factor-basic (rbFGF-basic) produced in E. coli is a single non-glycosylated polypeptide chain containing 146 amino acids. A fully biologically active molecule, rbFGF-basic has a molecular mass of 16.4 kDa analyzed by reducing SDS-PAGE.
Synonyms: FGF-2, BFGF, FGFB, HBGF-2 -
分子量
- 16.4 kDa, observed by reducing SDS-PAGE.
-
UniProt
- P03969
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
-