FGF6 Protein (AA 41-208)
FGF6
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
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- 抗原 See all FGF6 蛋白
- FGF6 (Fibroblast Growth Factor 6 (FGF6))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 41-208
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 产品特性
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ED50 < 2.5 ng/mL, measured by a cell proliferation assay using 3T3 cells in the presence 1 xg/mL heparin, corresponding to a specific activity of > 4x 10^5 units/mg.
AA 41-208, expressed with an N-terminal Met. - 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product FGF6 蛋白
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Fibroblast Growth Factor 6 (FGF6) (AA 41-208) protein (His tag)
FGF6 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant human Fibroblast Growth Factor-6 (rhFGF-6) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-6 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- FGF6 (Fibroblast Growth Factor 6 (FGF6))
- 别名
- Fibroblast Growth Factor-6 (FGF-6) (FGF6 产品)
- 别名
- FGF6 Protein, hst2 Protein, fgf-6 Protein, hbgf-6 Protein, HBGF-6 Protein, HST2 Protein, Fgf-6 Protein, HSTF-2 Protein, fgf4 Protein, fgf6 Protein, fibroblast growth factor 6 Protein, fibroblast growth factor 6a Protein, FGF6 Protein, fgf6 Protein, Fgf6 Protein, fgf6a Protein
- 背景
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Fibroblast Growth Factor-6 (FGF-6) is a cytokine belonging to the heparin-binding FGF family, and is structurally related to other members of FGF family, particularly FGF-4. In vivo, FGF-6 exhibits an expression profile predominantly restricted tothe myogenic lineage, and it preferentially binds to two of the FGF receptors: FGFR1 and FGFR4. FGF-6 functions in muscle regeneration, myoblast proliferation and migration, and muscle differentiation in a dose-dependent manner. In vivo high concentration of recombinant FGF-6 up-regulates and down-regulates FGFR1 and FGFR4, respectively, as FGFR1 promotes the proliferation while FGFR4 promotes the differentiation in the muscle. Besides its dual function in muscle regeneration, FGF-6 may act as a regulator of bone metabolism as well.Recombinant human Fibroblast Growth Factor-6 (rhFGF-6) produced in E. coli is a single non-glycosylated polypeptide chain containing 169 amino acids. A fully biologically active molecule, rhFGF-6 has a molecular mass of 18.8 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-6, HBGF-6, HST-2 - 分子量
- 18.8 kDa, observed by reducing SDS-PAGE.
- UniProt
- P10767
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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