FGF10 Protein (AA 62-209)
Quick Overview for FGF10 Protein (AA 62-209) (ABIN2017799)
抗原
See all FGF10 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 62-209
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产品特性
- ED50 < 10 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) protein (Biotin)
FGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 10 (FGF10) (AA 38-208) proteinFGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Tris-Bis PAGE
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His tag)FGF10 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmFGF-10 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
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有效期
- 6 months
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- FGF10 (Fibroblast Growth Factor 10 (FGF10))
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别名
- Fibroblast Growth Factor-10 (FGF-10)
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背景
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Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However, unlike KGF, which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development. Recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 148 amino acids. A fully biologically active molecule, rmFGF-10 has a molecular mass of 17.0 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2 -
分子量
- 17.0 kDa, observed by reducing SDS-PAGE.
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UniProt
- O35565
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
抗原
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