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FGF10 Protein (AA 62-209)

This Recombinant FGF10 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2017799
发货至: 中国
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Quick Overview for FGF10 Protein (AA 62-209) (ABIN2017799)

抗原

See all FGF10 蛋白
FGF10 (Fibroblast Growth Factor 10 (FGF10))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 13
  • 4
  • 3
小鼠

资源

  • 14
  • 2
  • 2
  • 1
大肠杆菌(E. Coli)

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 62-209

    产品特性

    ED50 < 10 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmFGF-10 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    有效期

    6 months
  • 抗原

    FGF10 (Fibroblast Growth Factor 10 (FGF10))

    别名

    Fibroblast Growth Factor-10 (FGF-10)

    背景

    Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However, unlike KGF, which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development. Recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 148 amino acids. A fully biologically active molecule, rmFGF-10 has a molecular mass of 17.0 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2

    分子量

    17.0 kDa, observed by reducing SDS-PAGE.

    UniProt

    O35565

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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