SNCA Protein (AA 1-140) (HiLyte Fluor 488)
Quick Overview for SNCA Protein (AA 1-140) (HiLyte Fluor 488) (ABIN1882766)
抗原
See all SNCA 蛋白蛋白类型
宿主
资源
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产品特性
- AA 1-140
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标记
- This SNCA protein is labelled with HiLyte Fluor 488.
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产品特性
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The recombinant human alpha-synuclein (1-140) was expressed and purified from E. coli and conjugated with the fluorescence dye HiLyte FluorTM 488.
Green fluorescence.
Excitation/Emission wavelengths= 503 nm/525 nm -
纯化方法
- Purified from E. Coli.
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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注意事项
- Protect from light!
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储存条件
- -80 °C
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- SNCA (Synuclein, alpha (SNCA))
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别名
- alpha-Synuclein
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背景
- Parkinson's disease (PD) is predominantly a movement disorder resulting from degeneration of dopaminergic neurons in the substantia nigra. The cause of the disease is unknown, but substantial evidence suggests that the aggregation of alpha-synuclein is a critical step in the etiology of PD. alpha-Synuclein is an abundant protein of 140 residues that is present in high concentration at presynaptic terminals and is found in both soluble and membrane-associated fractions of the brain. Several possible functions have been suggested, among which are vesicle release and trafficking. In vitro incubation in the presence of salt (i.e. 0.1 M NaCl) with agitation causes alpha-synuclein to form fibrils.
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NCBI登录号
- NP_000336
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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