Amphiregulin Protein (AREG) (AA 101-198)
Quick Overview for Amphiregulin Protein (AREG) (AA 101-198) (ABIN1692249)
抗原
See all Amphiregulin (AREG) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 101-198
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原理
- Recombinant Human Amphiregulin/AREG
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序列
- MSVRVEQVVK PPQNKTESEN TSDKPKRKKK GGKNGKNRRN RKKKNPCNAE FQNFCIHGEC KYIEHLEAVT CKCQQEYFGE RCGEKSMKTH SMIDSSLSK
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产品特性
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Recombinant Human Amphiregulin/AREG
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Amphiregulin (AREG) (Active) protein
AREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 101-187) protein (Fc Tag)AREG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-187) protein (Fc Tag)AREG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Amphiregulin (AREG)
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别名
- Amphiregulin/AREG
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背景
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Recombinant Human Amphiregulin/AREG is produced with our E. coli expression system. The target protein is expressed with sequence (Ser101-Lys198) of Human AREG.
Amphiregulin (AREG) is a single-pass membrane protein with 252 AAs. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor α (TGF-α). As an EGF-related growth factor, AREG interacts with the EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy. -
分子量
- 11.4 kDa
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UniProt
- P15514
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途径
- RTK signaling, EGFR Signaling Pathway
抗原
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