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SNCA Protein (AA 1-140)

This Recombinant SNCA protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1692153
发货至: 中国

Quick Overview for SNCA Protein (AA 1-140) (ABIN1692153)

抗原

See all SNCA 蛋白
SNCA (Synuclein, alpha (SNCA))

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-140

    原理

    Recombinant Human α-Synuclein/SNCA

    序列

    GSHMDVFMKG LSKAKEGVVA AAEKTKQGVA EAAGKTKEGV LYVGSKTKEG VVHGVATVAE KTKEQVTNVG GAVVTGVTAV AQKTVEGAGS IAAATGFVKK DQLGKNEEGA PQEGILEDMP VDPDNEAYEM PSEEGYQDYE PEA

    产品特性

    Recombinant Human Alpha-Synuclein/SNCA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala140) of Human SNCA.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
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    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    SNCA (Synuclein, alpha (SNCA))

    别名

    SNCA

    背景

    Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).
    Synonyms: Alpha-Synuclein, Non-A Beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1

    分子量

    14.7 kDa

    UniProt

    P37840

    途径

    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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