IL18R1 Protein (C-Term, Extracellular Domain)
(1 reference)Quick Overview for IL18R1 Protein (C-Term, Extracellular Domain) (ABIN1684708)
抗原
See all IL18R1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- C-Term, Extracellular Domain
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特异性
- Optimized DNA sequence encoding extracellular domain of Mouse IL-18 receptor including an C terminal IgG1 Fc tag was expressed in HEK293 cells.
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产品特性
- Recombinant mouse IL-18 receptor alpha is a homodimer protein consisting of two 555 amino acid residue subunits, due to glycosylation migrates as an approximately 95kD protein under reducing SDS-PAGE conditions.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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Interleukin 18 Receptor 1 (IL18R1) (AA 19-329) protein (His-Avi Tag)
IL18R1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Receptor 1 (IL18R1) (AA 22-329) protein (His tag)IL18R1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Receptor 1 (IL18R1) (AA 19-329) protein (His-Avi Tag,Biotin)IL18R1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Receptor 1 (IL18R1) (AA 20-326) protein (His tag)IL18R1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Receptor 1 (IL18R1) (AA 22-121) protein (GST tag)IL18R1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 18 Receptor 1 (IL18R1) (Active) protein (His tag,Fc Tag)IL18R1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Interleukin 18 Receptor 1 (IL18R1) protein (His tag)IL18R1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 18 Receptor 1 (IL18R1) protein (Fc Tag)IL18R1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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说明
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Biologically active: Measured by its ability to bind immobilized recombinant human IL-18 at a concentration range of 1-32 ng/mL in a functional ELISA assay.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS solution, pH7.2
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
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有效期
- 12-24 months
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: "Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 12, pp. 5781-8, (2015) (PubMed).
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: "Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 12, pp. 5781-8, (2015) (PubMed).
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- IL18R1 (Interleukin 18 Receptor 1 (IL18R1))
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别名
- IL18R1
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背景
- PDGF is synthesized mainly by megakaryocytes. It is stored in the alpha granules of platelets from which it is released after cell activation of platelets. Platelets synthesize a mixture of the three possible isoforms (BB,AB,AA) while fibroblasts stimulated with EGF synthesize AA homodimers. PDGF receptors are expressed in fibroblasts, osteoblasts, chondroblasts, smooth muscle cells, glial cells, and endothelial cells. Two related receptors, are PDGFRalpha (CD140a) or PDGFRbeta ( CD140b). In contrast to many other cytokines PDGF is not released into the circulation. PDGF binds to several plasma proteins and also to proteins of the extracellular matrix which facilitates local concentration of the factor. The factor functions as a local autocrine and paracrine growth factor. In the adult organism PDGF is involved in wound healing processes. The aberrant expression of PDGF is observed with vascular proliferative diseases such as atherosclerosis. PDGF regulates the synthesis of its own receptor and also influences the expression of membrane receptors for IL1, EGF, 5-Hydroxytryptamine, LDL, transferrin, and muscarinergic receptor.
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UniProt
- Q61098
抗原
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