EPOR Protein (C-Term, Extracellular Domain)
Quick Overview for EPOR Protein (C-Term, Extracellular Domain) (ABIN1684613)
抗原
蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- C-Term, Extracellular Domain
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特异性
- Optimized DNA sequence encoding extracellular domain of human erythropoietin receptor including a C-terminal Human IgG1 Fc tag was expressed in HEK293 cells.
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产品特性
- Recombinant EPO receptor is a homodimer protein consisting of two 460 amino acid residue subunit chains, due to glycosylation migrates as an approximately 55 kDa protein on SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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Erythropoietin Receptor (EPOR) (AA 25-138) protein (His-IF2DI Tag)
EPOR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Erythropoietin Receptor (EPOR) (AA 25-250) (Active) protein (His-Fc tag)EPOR 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
Erythropoietin Receptor (EPOR) (AA 1-508) protein (GST tag)EPOR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Erythropoietin Receptor (EPOR) (AA 25-250) protein (His tag)EPOR 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
Erythropoietin Receptor (EPOR) (Active) protein (His tag)EPOR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Erythropoietin Receptor (EPOR) (AA 25-250) (Active) protein (His tag)EPOR 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS, AcA Active
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说明
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The activity was tested by immobilized recombinant CD131 (10 µg/mL) ability to bind recombinant human EPOR with a range of 0.1-4 µg/mL.
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限制
- 仅限研究用
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缓冲液
- PBS solution, pH7.2
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- The lyophilized antibody is stable for at least 1 year from date of receipt at -20 °C. Upon reconstitution, this antibody can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months without detectable loss of activity.
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有效期
- 12 months
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- EPOR (Erythropoietin Receptor (EPOR))
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别名
- EPOR
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背景
- IL-7 is secreted constitutively into the conditioned medium of adherent bone marrow stromal cells and thymic cells. Mouse and human keratinocytes have been shown also to express and secrete IL7. Human (152 amino acids, 17.4 kDa) and murine IL7 (129 amino acids) show 60 % sequence homology at the protein level. The human IL7 receptor is an integral strongly glycosylated membrane proteins of 76 kDa expressed on activated T-cells. This receptor has been designated as CD127. IL7 receptors are expressed on pre-B-cells and their progenitors. They are not expressed on mature B-cells. IL7 receptors are expressed also on bone marrow macrophages. Functional IL7 receptors are found on the cell surface of multiphenotypic, biphenotypic, and immature lymphoid progenitors of B-cells with the gene arrangement of the heavy immunoglobulin chain such as those observed in the germ line
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UniProt
- P19235
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途径
- JAK/STAT Signaling
抗原
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