KDM5D Protein (His tag)
-
- 抗原 See all KDM5D 蛋白
- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 标记
- This KDM5D protein is labelled with His tag.
- 序列
- ALLVALQRLP VRLPEGEALQ CLTERAIGWQ DRARKALASE DVTALLRQLA ELRQQLQAKP RPEEASVYTS ATACDPIREG SGNNISKVQG LLENGDSVTS PENMAPGKGS DLELLSSLLP QLTGPVLELP EAIRAPLEEL MMEGDLLEVT LDENHSIWQL LQAGQPPDLD RIRTLLELEK FEHQGSRTRS RALERRRRRQ KVDQGRNVEN LVQQELQSKR ARSSGIMSQV GREEEHYQEK ADRENMFLTP STDHSPFLKG NQNSLQHKDS GSSAACPSLM PLLQLSYSDE QQLLEHHHHH H
- 产品特性
-
Length (AA): 301
Chromosomal location: Yq11, Yq11 - 纯度
- > 95 % by SDS-PAGE. Visualized by silver stain
- Top Product
- Discover our top product KDM5D 蛋白
-
Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 1-1548) protein (His tag)
custom-made KDM5D 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 1-1539) protein (His tag)custom-made KDM5D 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Lysine (K)-Specific Demethylase 5D (KDM5D) (AA 127-230) protein (GST tag)KDM5D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
-
- 应用备注
- Not tested so far.
- 说明
-
Cytokines & Growth Factors
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- The lyophilized human SMCY is supplied in lyophilized form and can be reconstituted in PBS or water. This solution can be diluted into other buffered solutions or stored frozen for future use.
- 缓冲液
- 50 mM NaP, 300 mM NaCl, pH 8.0
- 储存条件
- -20 °C/-80 °C
- 储存方法
- The lyophilized human SMCY, though stable at room temperature, is best stored in working aliquots at -20 °C to -70 °C.
-
- 抗原
- KDM5D (Lysine (K)-Specific Demethylase 5D (KDM5D))
- 别名
- SMCY/JARID1D (KDM5D 产品)
- 背景
-
H-Y antigen is defined as a male histocompatibility antigen that causes rejection of male skin grafts by female recipients of the same inbred strain of rodents. Male-specific, or H-Y antigen(s), are also detected by cytotoxic T cells and antibodies. H-Y antigen appears to be an integral part of the membrane of most male cells. In addition, H-Y antibodies detect a soluble form of H-Y that is secreted by the testis. The gene (Smcy/SMCY) coding for H-Y antigen detected by T cells has been cloned. It is expressed ubiquitously in male mice and humans, and encodes an epitope that triggers a specific T-cell response in vitro. Additional epitopes coded for by different Y-chromosomal genes are probably required in vivo for the rejection of male grafts by female hosts. The molecular nature of H-Y antigen detected by antibodies on most male cells is not yet known. Testis-secreted, soluble H-Y antigen, however, was found to be identical to Müllerian-inhibiting substance (MIS). MIS cross-reacts with H-Y antibodies and identical findings were obtained for soluble H-Y antigen and MIS, i.e., secretion by testicular Sertoli and, to a lesser degree, ovarian cells, binding to a gonad-specific receptor, induction of gonadal sex reversal in vitro and, in cattle, in vivo. H-Y antisera also detect a molecule or molecules associated with the heterogametic sex in non-mammalian vertebrates. Molecular data on this antigen or antigens are not yet available.
Synonyms: KDM5D lysine (K)-specific demethylase 5D, HY, HYA - 分子量
- 33.87 kDa
- NCBI登录号
- NM_001146705, NP_001140177
- UniProt
- Q9BY66
- 途径
- Warburg Effect
-
