电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MANF 蛋白

MANF 宿主: 人 宿主: CHO Cells Recombinant WB, SDS, CC, in vivo Active
产品编号 ABIN1405920
发货至: 中国
  • 抗原 See all MANF 蛋白
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 2
    • 1
    • 1
    资源
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    CHO Cells
    应用范围
    Western Blotting (WB), SDS-PAGE (SDS), Cell Culture (CC), In vivo Studies (in vivo)
    产品特性
    Bio-activity testing: Protein is biologically active. Suitable for cell culture and in vivo testing. Human recombinant MANF has been tested in rat &-OHDA model of Parkinson's disease and shown neureprotection and neurorestoration. MANF has also shown neuroprotection in animal models of stroke
    纯化方法
    Purified by ion-exchange chromatography and gel-filtration from serum-free CHO growth media.
    Purified Protein is characterized as homogenous material by mass-spectroscopy.
    内毒素水平
    Less than 1EU/µg of protein as determined by LAL method
    Top Product
    Discover our top product MANF 蛋白
  • 说明

    Synonyms: Mesencephalic astrocyte-derived neurotrophic factor - MANF, ARMET, ARP

    限制
    仅限研究用
  • 浓度
    1 mg/ml Concentration of the protein is determined by BCA Protein Analysis kit (Pierce). BSA was used as a standard
    缓冲液
    PBS pH 7.4
    注意事项
    Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles.
    储存条件
    -80 °C
  • 抗原
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    别名
    MANF (MANF 产品)
    别名
    ARMET Protein, ARP Protein, 3230402M22Rik Protein, AA407711 Protein, AA408789 Protein, AA673178 Protein, Armet Protein, D17914 Protein, D18Mgi17 Protein, MANF Protein, RBM15B Protein, ARP-like Protein, CG7013 Protein, DmMANF Protein, Dmel\\CG7013 Protein, anon-EST:ParkEST188 Protein, arp Protein, armet Protein, im:6909481 Protein, zgc:153327 Protein, manf Protein, mesencephalic astrocyte derived neurotrophic factor Protein, mesencephalic astrocyte-derived neurotrophic factor Protein, RNA binding motif protein 15B Protein, Mesencephalic astrocyte-derived neurotrophic factor Protein, mesencephalic astrocyte-derived neurotrophic factor S homeolog Protein, MANF Protein, Manf Protein, RBM15B Protein, manf Protein, manf.S Protein
    背景
    MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson’s disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
    分子量
    Approximately 18.1 kDa, a single non-glycosylated polypeptide chain containing 163 amino acids.
    UniProt
    P55145
You are here:
客服