Annexin V Protein (GST tag)
Quick Overview for Annexin V Protein (GST tag) (ABIN1344454)
抗原
See all Annexin V (ANXA5) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Annexin V protein is labelled with GST tag.
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原理
- Annexin V (human) (rec.)
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特异性
- Binds to phosphatidylserine (PS).
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交叉反应
- 人
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产品特性
- Recombinant human annexin V fused to a GST-tag.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with 100 μL sterile water.
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浓度
- 1 mg/mL
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缓冲液
- In PBS.
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注意事项
- Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. Repeated freeze/thaw cycles (>3) may result in an adverse effect on the activity.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.
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有效期
- 12 months
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Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).
: "
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Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).
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- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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别名
- Annexin V
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背景
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Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
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分子量
- ~52kDa (SDS-PAGE)
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UniProt
- P08758
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途径
- Apoptosis
抗原
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