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Annexin V Protein (GST tag)

This anti-Annexin V antibody (ABIN1344454) is a Escherichia coli (E. coli) antibody detecting Annexin V in SDS. Suitable for Human.
产品编号 ABIN1344454
发货至: 中国

Quick Overview for Annexin V Protein (GST tag) (ABIN1344454)

抗原

See all Annexin V (ANXA5) 蛋白
Annexin V (ANXA5) (Annexin A5 (ANXA5))

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

>95 % (SDS-PAGE)
  • 标记

    This Annexin V protein is labelled with GST tag.

    原理

    Annexin V (human) (rec.)

    特异性

    Binds to phosphatidylserine (PS).

    交叉反应

    产品特性

    Recombinant human annexin V fused to a GST-tag.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with 100 μL sterile water.

    浓度

    1 mg/mL

    缓冲液

    In PBS.

    注意事项

    Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. Repeated freeze/thaw cycles (>3) may result in an adverse effect on the activity.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.

    有效期

    12 months
  • Morizono, Chen: "Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).

  • 抗原

    Annexin V (ANXA5) (Annexin A5 (ANXA5))

    别名

    Annexin V

    背景

    Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha

    Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

    分子量

    ~52kDa (SDS-PAGE)

    UniProt

    P08758

    途径

    Apoptosis
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