DLK1 Protein (AA 1-303) (DYKDDDDK Tag)
-
- 抗原 See all DLK1 蛋白
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-303
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This DLK1 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 原理
- DLK1 (human) (rec.)
- 交叉反应
- 人
- 产品特性
- Signal peptide and extracellular domain of human DLK1 (aa 1-303) are fused at the C-terminus to a FLAG®-tag.
- 纯度
- >90 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product DLK1 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 缓冲液
- Contains PBS.
- 注意事项
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. PBS containing at least 0.1 % BSA should be used for further dilutions.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- 有效期
- 6 months
-
- 抗原
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- 别名
- DLK1 (DLK1 产品)
- 背景
-
Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
- 分子量
- ~40kDa (SDS-PAGE)
- UniProt
- P80370
-