MOG Protein (AA 30-154)
This Recombinant MOG protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for MOG Protein (AA 30-154) (ABIN1097171)
抗原
See all MOG 蛋白
MOG
(Myelin Oligodendrocyte Glycoprotein (MOG))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
Functional Studies (Func)
纯度
> 95 % as determined by reducing SDS-PAGE.
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产品特性
- AA 30-154
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原理
- Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG
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序列
- MGQFRVIGPR HPIRALVGDE VELPCRISPG KNATGMEVGW YRPPFSRVVH LYRNGKDQDG DQAPEYRGRT ELLKDAIGEG KVTLRIRNVR FSDEGGFTCF FRDHSYQEEA AMELKVEDPF YWVSPGHHHH HH
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产品特性
- Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG is produced with our E. coli expression system. The target protein is expressed with sequence (Gly30-Gly154) of Human MOG protein.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Myelin Oligodendrocyte Glycoprotein (MOG) (AA 30-154) protein (His tag)
MOG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Myelin Oligodendrocyte Glycoprotein (MOG) (AA 1-295) protein (GST tag)MOG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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说明
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Biological activity: Tested for capability to induce EAE in rodents and monkeys
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
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别名
- mog-protein
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背景
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Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG -
分子量
- 15.2 kDa
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UniProt
- Q16653
抗原
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