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MOG Protein (AA 30-154)

This Recombinant MOG protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1097170
发货至: 中国
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Quick Overview for MOG Protein (AA 30-154) (ABIN1097170)

抗原

See all MOG 蛋白
MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 13
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资源

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大肠杆菌(E. Coli)

应用范围

Functional Studies (Func)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 30-154

    原理

    Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG

    序列

    MGQFRVIGPR HPIRALVGDE VELPCRISPG KNATGMEVGW YRPPFSRVVH LYRNGKDQDG DQAPEYRGRT ELLKDAIGEG KVTLRIRNVR FSDEGGFTCF FRDHSYQEEA AMELKVEDPF YWVSPGHHHH HH

    产品特性

    Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG is produced with our E. coli expression system. The target protein is expressed with sequence (Gly30-Gly154) of Human MOG protein.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 说明

    Biological activity: Tested for capability to induce EAE in rodents and monkeys

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

    别名

    mog-protein

    背景

    Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
    Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG

    分子量

    15.2 kDa

    UniProt

    Q16653
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