IL-11 蛋白
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- 抗原 See all IL-11 (IL11) 蛋白
- IL-11 (IL11) (Interleukin 11 (IL11))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Yeast (Pichia pastoris)
- 应用范围
- Functional Studies (Func)
- 原理
- Recombinant Human Interleukin-11/IL-11
- 序列
- GPPPGPPRVS PDPRAELDST VLLTRSLLAD TRQLAAQLRD KFPADGDHNL DSLPTLAMSA GALGALQLPG VLTRLRADLL SYLRHVQWLR RAGGSSLKTL EPELGTLQAR LDRLLRRLQL LMSRLALPQP PPDPPAPPLA PPSSAWGGIR AAHAILGGLH LTLDWAVRGL LLLKTRL
- 产品特性
- Recombinant Human Interleukin-11/IL-11 is produced in P. pastoris by recombinant DNA technology. The protein has a molecular mass of approximately 19,0 kDa and is non-glycosylated. The protein is 177 amino acids in length and differs from the 178 amino acid length of native IL-11 by lacking the amino-terminal praline residue.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IL11 蛋白
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Interleukin 11 (IL11) (AA 22-199) protein (His tag)
IL11 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 宿主: 人 宿主: 大肠杆菌（E. Coli） > 90 % AcA, CC Active
Interleukin 11 (IL11) (Active) proteinIL11 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 11 (IL11) protein (Fc Tag)IL11 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 11 (IL11) (AA 1-199) protein (GST tag)IL11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) (AA 25-74) protein (GST tag)IL11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) proteinIL11 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant
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- 说明
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Biological activity: ED50 is less than 0.2 ng/ml as determined by the dose-dependent stimulation of murine 7TD1 proliferation.Specific Activity of 8.0 x 106 IU/ mg.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- IL-11 (IL11) (Interleukin 11 (IL11))
- 别名
- il-11 (IL11 产品)
- 别名
- IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
- 背景
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Interleukin 11 (IL-11) is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. IL-11 is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors.
Alternative Names: Interleukin-11, IL-11, Adipogenesis Inhibitory Factor, AGIF, Oprelvekin, IL11 - 分子量
- 19 kDa
- UniProt
- P20809
- 途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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