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CXCL14 蛋白

This Recombinant CXCL14 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1096464
发货至: 中国
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Quick Overview for CXCL14 蛋白 (ABIN1096464)

抗原

See all CXCL14 蛋白
CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 9
  • 4
  • 3

资源

  • 14
  • 1
  • 1
大肠杆菌(E. Coli)

应用范围

Functional Studies (Func)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human C-X-C Motif Chemokine 14/CXCL14

    序列

    SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE

    产品特性

    Recombinant Human C-X-C Motif Chemokine Ligand 14/CXCL14 produced in E. coli is a single non-glycosylated polypeptide chain containing 77 amino acids with a molecular mass of 9.4 kDa.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 说明

    Biological activity: ED50 is 1.0-10.0 ng/ml as determined by the ability of Recombinant CXCL14 to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 1M NaCl, pH 8.5.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    3 months
  • 抗原

    CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))

    别名

    cxcl14

    背景

    Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
    Alternative Names: C-X-C Motif Chemokine 14, Chemokine BRAKm MIP-2G, Small-Inducible Cytokine B14, CXCL14, MIP2G, NJAC, SCYB14

    分子量

    9.4 kDa

    UniProt

    O95715

    途径

    Autophagy
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