CCL5 Protein (AA 24-91)
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北京 101111
Quick Overview for CCL5 Protein (AA 24-91) (ABIN1096283)
抗原
See all CCL5 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 24-91
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原理
- Recombinant Human C-C Motif Chemokine 5/CCL5/RANTES
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序列
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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产品特性
- Recombinant Human C-C Motif Chemokine 5/CCL5 is produced by E. coli transformed with a plasmid containing sequence (Ser24-Met91) of Human CCL5.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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别名
- CCL5/RANTES
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背景
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Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
Alternative Names: C-C Motif Chemokine 5, EoCP, Eosinophil Chemotactic Cytokine, SIS-Delta, Small-Inducible Cytokine A5, T Cell-Specific Protein P228, TCP228, T-Cell-Specific Protein RANTES, CCL5, D17S136E, SCYA5 -
分子量
- 7.8 kDa
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UniProt
- P13501
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
抗原
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