CCL16 蛋白
Quick Overview for CCL16 蛋白 (ABIN1096260)
抗原
See all CCL16 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human C-C Motif Chemokine 16/CCL16
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序列
- QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ
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产品特性
- Recombinant Human C-C Motif Chemokine 16/CCL16 produced by E. coli is a single non-glycosylated polypeptide chain containing 97 amino acids with a molecular mass of 11.0 kDa.
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His-IF2DI Tag)
CCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)CCL16 宿主: 人 宿主: Yeast (Pichia pastoris) Recombinant > 95 % SDS, WB, ELISA, IP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His-SUMO Tag)CCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
有效期
- 3 months
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- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
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别名
- CCL16/HCC-4
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背景
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CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
Alternative Names: C-C Motif Chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-Inducible Chemokine, LCC-1, Liver-Expressed Chemokine, Lymphocyte and Monocyte Chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-Inducible Cytokine A16, CCL16, ILINCK, NCC4, SCYA16 -
分子量
- 11 kDa
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UniProt
- O15467
抗原
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