CCL16 蛋白
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- 抗原 See all CCL16 蛋白
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed.
- 产品特性
- Extracellular Domain Protein
- Top Product
- Discover our top product CCL16 蛋白
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Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)
CCL16 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 25-120) protein (GST tag)CCL16 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)CCL16 宿主: 人 宿主: Yeast (Pichia pastoris) Recombinant > 95 % SDS, WB, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C
- 储存方法
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- 别名
- CCL16 (CCL16 产品)
- 别名
- CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
- 背景
- C-C Motif Chemokine 16, Chemokine CC-4, HCC-4, Chemokine LEC, IL-10-Inducible Chemokine, LCC-1, Liver-Expressed Chemokine, Lymphocyte and Monocyte Chemoattractant, LMC, Monotactin-1, MTN-1, NCC-4, Small-Inducible Cytokine A16, CCL16, ILINCK, NCC4, SCYA16CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30 % sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
- 分子量
- 11 KDa
- UniProt
- O15467
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