Ring Finger Protein 8 抗体
(Ring Finger Protein 8 (RNF8))
The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
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57 results
RNF8
适用: 人, 小鼠, 大鼠, Cow, 马, Pig, Bat, 猴
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
2 images
Latest Publications for our Ring Finger Protein 8 抗体
: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).
: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." in: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).
: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." in: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).
Aliases for Ring Finger Protein 8 抗体
ring finger protein 8 (RNF8) 抗体ring finger protein 8 (Rnf8) 抗体
ring finger protein 8, E3 ubiquitin protein ligase S homeolog (rnf8.S) 抗体
ring finger protein 8, E3 ubiquitin protein ligase L homeolog (rnf8.L) 抗体
ring finger protein 8, E3 ubiquitin protein ligase (rnf8) 抗体
3830404E21Rik 抗体
AIP37 抗体
fc66f09 抗体
hRNF8 抗体
RNF8 抗体
rnf8 抗体
wu:fc66f09 抗体
zgc:55936 抗体
zgc:77313 抗体
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