RNF8 抗体 (C-Term)
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北京 101111
Quick Overview for RNF8 抗体 (C-Term) (ABIN2778597)
抗原
See all RNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- RNF8 Antibody - C-terminal region
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序列
- MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE
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预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40071-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RNF8 (Ring Finger Protein 8 (RNF8))
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别名
- RNF8
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背景
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Background Information: RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene Name: Ring finger protein 8, E3 ubiquitin protein ligase
Alternative Symbols: hRNF8
Protein Name: E3 ubiquitin-protein ligase RNF8
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分子量
- 55kDa
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基因ID
- 9025
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NCBI登录号
- NP_003949
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UniProt
- O76064
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途径
- Production of Molecular Mediator of Immune Response
抗原
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