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PRTN3 产品

(Proteinase 3 (PRTN3))

Categories

Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

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Featured PRTN3 Categories

PRTN3 抗体

High quality antibodies with extensive validation data.

PRTN3 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PRTN3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRTN3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7433627
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN1781866
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7433630
Quantity 100 μL
Datasheet Datasheet

Recommended PRTN3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958968
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6974113
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969763
Quantity 96 tests
Datasheet Datasheet

Recommended PRTN3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316494
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316492
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086664
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PRTN3 Products

Kolonin, Sergeeva, Staquicini, Smith, Tarleton, Molldrem, Sidman, Marchiò, Pasqualini, Arap: "Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone." in: Cancer research, Vol. 77, Issue 12, pp. 3144-3150, (2017) (PubMed).

Wu, Liu, Chen, Chen, Zhang: "Disequilibrium of Blood Coagulation and Fibrinolytic System in Patients With Coronary Artery Ectasia." in: Medicine, Vol. 95, Issue 8, pp. e2779, (2016) (PubMed).

Salgado, Pereiro, López-Doval, Lafuente: "Initial study on the possible mechanisms involved in the effects of high doses of perfluorooctane sulfonate (PFOS) on prolactin secretion." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 83, pp. 10-16, (2015) (PubMed).

Türko?lu, Azars?z, Emingil, Kütükçüler, Atilla: "Are proteinase 3 and cathepsin C enzymes related to pathogenesis of periodontitis?" in: BioMed research international, Vol. 2014, pp. 420830, (2014) (PubMed).

Hao, Wang, Yuan, Chen, Zhao: "A pro-inflammatory role of C5L2 in C5a-primed neutrophils for ANCA-induced activation." in: PLoS ONE, Vol. 8, Issue 6, pp. e66305, (2013) (PubMed).

Bae, Kang, Hong, Lee, Choi, Jhun, Kwak, Hong, Kim, Jo, Kim: "Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 8205-13, (2012) (PubMed).

Kuhl, Korkmaz, Utecht, Kniepert, Schönermarck, Specks, Jenne: "Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 387-99, (2010) (PubMed).

Abdgawad, Gunnarsson, Bengtsson, Geborek, Nilsson, Segelmark, Hellmark: "Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression." in: Clinical and experimental immunology, Vol. 161, Issue 1, pp. 89-97, (2010) (PubMed).

Hajjar, Broemstrup, Kantari, Witko-Sarsat, Reuter: "Structures of human proteinase 3 and neutrophil elastase--so similar yet so different." in: The FEBS journal, Vol. 277, Issue 10, pp. 2238-54, (2010) (PubMed).

Källquist, Rosén, Nordenfelt, Calafat, Janssen, Persson, Hansson, Olsson: "Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells." in: Experimental cell research, Vol. 316, Issue 19, pp. 3182-96, (2010) (PubMed).

Synonyms and alternative names related to PRTN3

proteinase 3 L homeolog (prtn3.L), proteinase 3 (PRTN3), proteinase 3 (Prtn3), ACPA, AGP7, C-ANCA, CANCA, ela2, MBN, MBT, MGC132250, mPR3, NP-4, NP4, P29, PR-3, PR3

Protein level used designations for PRTN3

  • proteinase 3
  • C-ANCA antigen
  • Wegener granulomatosis autoantigen
  • azurophil granule protein 7
  • leukocyte proteinase 3
  • myeloblastin
  • neutrophil proteinase 4
  • serine proteinase, neutrophil
  • wegener autoantigen
  • PR-3
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