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PRKAB2 蛋白

(Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq, Jul 2008].

Popular PRKAB2 蛋白

Aliases for PRKAB2 蛋白

protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog (prkab2.L) 蛋白
protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2) 蛋白
protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2) 蛋白
protein kinase, AMP-activated, beta 2 non-catalytic subunit (prkab2) 蛋白
protein kinase, AMP-activated, beta 2 non-catalytic subunit (Prkab2) 蛋白
protein kinase AMP-activated non-catalytic subunit beta 2 (Prkab2) 蛋白
5730553K21Rik 蛋白
AW049591 蛋白
BB124140 蛋白
DKFZp469M1118 蛋白
MGC64365 蛋白
prkab2 蛋白
PRKAB2 蛋白
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