PPM1F 蛋白
(Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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10 results
PPM1F
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
custom-made
PPM1F
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
PPM1F
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
PPM1F
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Rockland Original
Aliases for PPM1F 蛋白
protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F) 蛋白protein phosphatase 1F (PP2C domain containing) (Ppm1f) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1F (Ppm1f) 蛋白
1110021B16Rik 蛋白
4933427B07Rik 蛋白
CAMKP 蛋白
CaMKPase 蛋白
FEM-2 蛋白
hFEM-2 蛋白
mKIAA0015 蛋白
Popx2 蛋白
POPX2 蛋白
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