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PPM1D 蛋白

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (His tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (His tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (His tag) (ABIN3086448)

Crystallography grade PPM1D 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-598) protein (His tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-598) protein (His tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-598) protein (His tag) (ABIN3130585)

Crystallography grade PPM1D 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (GST tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (GST tag) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (GST tag) (ABIN1315909)

PPM1D 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB

PPM1D 蛋白 by Grade

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PPM1D 蛋白 by Origin

Find PPM1D 蛋白 for a variety of species such as anti-Human PPM1D, anti-Mouse PPM1D. The species listed below are among those available. Click on a link to go to the corresponding products.

PPM1D 蛋白 by Source

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PPM1D 蛋白 by 蛋白类型

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PPM1D 蛋白 by 应用范围

Find PPM1D 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PPM1D 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729806
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623952
Quantity 50 μg
Datasheet Datasheet

Aliases for PPM1D 蛋白

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) 蛋白
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) 蛋白
AV338790 蛋白
PP2C-DELTA 蛋白
ppm1d 蛋白
WIP1 蛋白
Wip1 蛋白
wu:fj44c08 蛋白
zgc:55836 蛋白
zgc:77316 蛋白
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