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抗Rat (Rattus) 抗体:
抗Mouse (Murine) 抗体:
human epidermal growth factor receptor (显示 EGFR 抗体) 2 (HER-2 (显示 ERBB2 抗体)) levels, were correlated well with TSP50 (显示 PRSS50 抗体)/p-Samd2 (显示 SARM1 抗体)/3 and TSP50 (显示 PRSS50 抗体)/p27 (显示 PAK2 抗体) expression status. Thus, our studies revealed a novel regulatory mechanism underlying TSP50 (显示 PRSS50 抗体)-induced cell proliferation and provided a new favorable intervention target for the treatment of breast cancer
Furthermore, inhibition of COPS5 (显示 COPS5 抗体) resulted in an elevation of Akt (显示 AKT1 抗体) expression and sensitized SOC (显示 UBXN11 抗体) cells to Akt (显示 AKT1 抗体) inhibitor MK2206. Suppression of COPS5 (显示 COPS5 抗体) and Akt (显示 AKT1 抗体) offers a potential strategy for the treatment of SOC (显示 UBXN11 抗体).
Loss of p27 (显示 PAK2 抗体) associated with risk for endometrial carcinoma arising in the setting of obesity.
p53 (显示 TP53 抗体) immunopositivity was more frequent in SCC (显示 CYP11A1 抗体) (65%) than in VC (23%) (P=0.001). VC had lower p53 (显示 TP53 抗体) as compared with well-differentiated SCC (显示 CYP11A1 抗体) and SCC (显示 CYP11A1 抗体) without lymph node metastasis. No significant difference was seen in pRb (显示 RB1 抗体), p16, and p27 (显示 PAK2 抗体) expression
The PSMD9 intronic SNPs rs74421874 (IVS3+nt460 G>A) and rs3825172 (IVS3+nt437 C>T) remain significantly associated with insomnia only when taking into account anxiety -and not depression- as covariate.
Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit (显示 PSMD14 抗体) 9 (显示 ATP5G1 抗体) (PSMD9), proteasome alpha type 7 (显示 PSMA7 抗体) subunit (PSMA7 (显示 PSMA7 抗体)) and PSMD13 (显示 PSMD13 抗体) genes.
recurrence rate of p27 and/or PTEN-negative patients was higher than that of the positive ones,that should be followed up closely after treatment
The present study provided the first evidences that miR (显示 MLXIP 抗体)-1470 mediated lapatinib induced p27 (显示 PAK2 抗体) upregulation by targeting c-jun (显示 JUN 抗体).
Staining intensities of cell cycle inhibitors p27 (显示 PAK2 抗体) and p57 (显示 CDKN1C 抗体) significantly increased in all parts of preeclamptic placentas compared to control
PSMD9 expression predicts radiotherapy response in breast cancer.
These results therefore suggest that proteasomes, particularly p27 (显示 CDKN1B 抗体) subunit, are directly involved in the regulation of melanin biosynthesis in mouse melanoma cells.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.
26S proteasome non-ATPase regulatory subunit 9
, 26S proteasome regulatory subunit p27
, homolog of rat Bridge 1
, proteasome 26S non-ATPase regulatory subunit 9
, transactivating protein Bridge-1
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
, proteasome 26S non-ATPase subunit 9
, PDZ domain-containing protein