This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
custom-made
POU6F2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
POU6F2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
POU class 6 homeobox 2 (POU6F2) 蛋白 POU domain, class 6, transcription factor 2 (Pou6f2) 蛋白 POU domain, class 6, transcription factor 2 (LOC483249) 蛋白 POU class 6 homeobox 2 (Pou6f2) 蛋白 POU class 6 homeobox 2 (pou6f2) 蛋白 D130006K24Rik 蛋白 RPF-1 蛋白 si:ch211-124o16.3 蛋白 WT5 蛋白 WTSL 蛋白