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POU6F2 产品

(POU Class 6 Homeobox 2 (POU6F2))

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This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

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Featured POU6F2 Categories

POU6F2 抗体

High quality antibodies with extensive validation data.

POU6F2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

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Latest Publications for our POU6F2 Products

Perotti, De Vecchi, Testi, Lualdi, Modena, Mondini, Ravagnani, Collini, Di Renzo, Spreafico, Terenziani, Sozzi, Fossati-Bellani, Radice: "Germline mutations of the POU6F2 gene in Wilms tumors with loss of heterozygosity on chromosome 7p14." in: Human mutation, Vol. 24, Issue 5, pp. 400-7, (2004) (PubMed).

Synonyms and alternative names related to POU6F2

POU class 6 homeobox 2 (POU6F2), POU domain, class 6, transcription factor 2 (Pou6f2), POU domain, class 6, transcription factor 2 (LOC483249), POU class 6 homeobox 2 (Pou6f2), POU class 6 homeobox 2 (pou6f2), D130006K24Rik, RPF-1, si:ch211-124o16.3, WT5, WTSL

Protein level used designations for POU6F2

  • POU domain, class 6, transcription factor 2
  • Wilms tumor suppressor locus
  • retina-derived POU domain factor 1
  • retina-derived POU-domain factor-1
  • POU class 6 homeobox 2
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