POT1 蛋白
(Protection of Telomeres 1 (POT1))
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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8 results
POT1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
2 references
custom-made
POT1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
POT1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Latest Publications for our POT1 蛋白
: "An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity." in: PLoS ONE, Vol. 11, Issue 5, pp. e0156378, (2016) (PubMed).: "The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs." in: Biochimie, Vol. 115, pp. 17-27, (2015) (PubMed).
Aliases for POT1 蛋白
protection of telomeres 1 (POT1) 蛋白protection of telomeres 1 L homeolog (pot1.L) 蛋白
protection of telomeres 1A (Pot1a) 蛋白
protection of telomeres 1 (Pot1) 蛋白
1500031H18Rik 蛋白
AI851169 蛋白
DKFZp469P1825 蛋白
HPOT1 蛋白
POT1 蛋白
pot1 蛋白
Pot1 蛋白
Pot1a 蛋白
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