Poly-U Binding Splicing Factor 60KDa 蛋白
(Poly-U Binding Splicing Factor 60KDa (PUF60))
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].
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custom-made
PUF60
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
PUF60
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
custom-made
PUF60
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Latest Publications for our Poly-U Binding Splicing Factor 60KDa 蛋白
: "PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome." in: Annals of the rheumatic diseases, Vol. 75, Issue 6, pp. 1145-51, (2016) (PubMed).
Aliases for Poly-U Binding Splicing Factor 60KDa 蛋白
poly(U) binding splicing factor 60 (PUF60) 蛋白poly-U binding splicing factor a (puf60a) 蛋白
poly-U binding splicing factor 60 (Puf60) 蛋白
poly(U) binding splicing factor 60 (Puf60) 蛋白
poly-U binding splicing factor b (puf60b) 蛋白
2410104I19Rik 蛋白
2810454F19Rik 蛋白
fc21a05 蛋白
fe37c05 蛋白
FIR 蛋白
repressor 蛋白
RoBPI 蛋白
si:ch211-12p8.2 蛋白
si:zc12p8.2 蛋白
SIAHBP1 蛋白
Siahbp1 蛋白
wu:fb33e11 蛋白
wu:fc21a05 蛋白
wu:fe37c05 蛋白
wu:fi43a08 蛋白
zgc:86806 蛋白
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