POLK 抗体
(Polymerase (DNA Directed) kappa (POLK))
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]).[supplied by OMIM, Jan 2010].
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54 results
Rockland 600-101-295
POLK
适用: 人
WB, ELISA
宿主: 山羊
Polyclonal
unconjugated
1 image
Rockland Original
Latest Publications for our POLK 抗体
: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).: "Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
: "Crystal structure of the catalytic core of human DNA polymerase kappa." in: Structure (London, England : 1993), Vol. 12, Issue 8, pp. 1395-404, (2004) (PubMed).
: "Translesion synthesis past 2'-deoxyxanthosine, a nitric oxide-derived DNA adduct, by mammalian DNA polymerases." in: Journal of molecular biology, Vol. 344, Issue 3, pp. 665-74, (2004) (PubMed).
: "A mechanism for the exclusion of low-fidelity human Y-family DNA polymerases from base excision repair." in: Genes & development, Vol. 17, Issue 22, pp. 2777-85, (2003) (PubMed).
Aliases for POLK 抗体
DNA polymerase kappa (POLK) 抗体DNA polymerase kappa (Polk) 抗体
polymerase (DNA directed) kappa (polk) 抗体
DNA polymerase kappa (Tb11.01.0080) 抗体
DNA polymerase kappa (Tb11.01.0010) 抗体
DNA polymerase kappa (Tb11.01.0020) 抗体
DNA polymerase kappa (Tb11.01.0030) 抗体
DNA polymerase kappa (Tb11.01.0040) 抗体
DNA polymerase kappa (Tb11.01.0050) 抗体
DNA polymerase kappa (Tb11.12.0001) 抗体
DNA polymerase kappa (Tb11.12.0002) 抗体
DNA polymerase kappa (Tb11.12.0003) 抗体
polymerase (DNA directed), kappa (Polk) 抗体
polymerase (DNA directed) kappa L homeolog (polk.L) 抗体
DNA polymerase kappa (polk-1) 抗体
DINB1 抗体
Dinb1 抗体
DINP 抗体
POLK 抗体
POLQ 抗体
si:ch211-254o18.3 抗体
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