POLI 抗体
(Polymerase (DNA Directed) iota (POLI))
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity (By similarity).
Recommended next Filters:
您想试用我们的人工智能搜索吗？
52 results :
POLI
适用: 人, 大鼠, 小鼠
WB, ELISA, IHC, IF, ICC
宿主: 兔
Polyclonal
unconjugated
POLI
适用: 大鼠
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
1 image
POLI
适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig
WB
宿主: 兔
Polyclonal
unconjugated
1 image
POLI
适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 兔, Saccharomyces cerevisiae
WB
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our POLI 抗体
: "DNA polymerase ι is acetylated in response to SN2 alkylating agents." in: Scientific reports, Vol. 9, Issue 1, pp. 4789, (2019) (PubMed).: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
: "Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
: "Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin." in: Nature communications, Vol. 5, pp. 5437, (2014) (PubMed).
: "DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity." in: Nucleic acids research, Vol. 40, Issue 1, pp. 170-80, (2011) (PubMed).
: "Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation." in: Journal of nucleic acids, Vol. 2010, pp. 750296, (2010) (PubMed).
: "DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 28, pp. 11552-7, (2009) (PubMed).
: "Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations." in: Cancer research, Vol. 67, Issue 7, pp. 3018-26, (2007) (PubMed).
: "The role of DNA polymerase iota in UV mutational spectra." in: Mutation research, Vol. 599, Issue 1-2, pp. 58-65, (2006) (PubMed).
: "Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template." in: The EMBO journal, Vol. 20, Issue 11, pp. 2914-22, (2001) (PubMed).
Aliases for POLI 抗体
DNA polymerase iota (POLI) 抗体polymerase (DNA directed) iota (poli) 抗体
DNA polymerase iota (LOC551219) 抗体
DNA polymerase iota (AFUA_4G11140) 抗体
DNA polymerase iota (LOC5568276) 抗体
polymerase (DNA directed) iota (Pol-iota) 抗体
polymerase (DNA directed), iota (Poli) 抗体
DNA polymerase iota (Poli) 抗体
GB12093 抗体
NV16187 抗体
poli 抗体
RAD3OB 抗体
RAD30B 抗体
Rad30b 抗体
wu:fc27h11 抗体
zgc:110185 抗体
您还需要查找其他产品吗？
You are here:
