PLOD1 抗体
(Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008].
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19 results
PLOD1
适用: 人
WB, FACS, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our PLOD1 抗体
: "Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 8, pp. 4459-4469, (2019) (PubMed).: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." in: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).
: "Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation." in: PLoS genetics, Vol. 12, Issue 4, pp. e1006002, (2016) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve." in: Journal of the American Heart Association, Vol. 2, Issue 1, pp. e000034, (2013) (PubMed).
Aliases for PLOD1 抗体
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) 抗体procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (Plod1) 抗体
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1) 抗体
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (Plod1) 抗体
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