PLOD1 抗体 (AA 23-640)
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Quick Overview for PLOD1 抗体 (AA 23-640) (ABIN7872549)
抗原
See all PLOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-640
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原理
- PLOD1 Antibody / Lysyl hydroxylase 1 / LH1
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids K23-A640) was used as the immunogen for the PLOD1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PLOD1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PLOD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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别名
- PLOD1
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背景
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q02809
抗原
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