PLEKHG6 蛋白
(Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
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6 results
custom-made
PLEKHG6
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
PLEKHG6
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
PLEKHG6
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for PLEKHG6 蛋白
pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6) 蛋白pleckstrin homology domain containing, family G (with RhoGef domain) member 6 (Plekhg6) 蛋白
BC026778 蛋白
Gm155 蛋白
MyoGEF 蛋白
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