PLEKHO1 蛋白
(Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation (By similarity).
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custom-made
PLEKHO1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
PLEKHO1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for PLEKHO1 蛋白
pleckstrin homology domain containing O1 (PLEKHO1) 蛋白pleckstrin homology domain containing, family O member 1 (Plekho1) 蛋白
pleckstrin homology domain containing O1 (Plekho1) 蛋白
pleckstrin homology domain containing, family O member 1a (plekho1a) 蛋白
2810052M02Rik 蛋白
CKIP-1 蛋白
ckip-1 蛋白
Ckip1 蛋白
JZA-20 蛋白
Jza2 蛋白
OC120 蛋白
plekho1 蛋白
RGD1311487 蛋白
si:dkey-200h23.2 蛋白
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