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PLCE1 蛋白

(Phospholipase C, epsilon 1 (PLCE1))
This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome\; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009].

4 results :

PLCE1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7422847
 
PLCE1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7420075
 
PLCE1 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC
产品编号 ABIN7420078
 
PLCE1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2729133
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Immunogen (Imm)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Mouse
    • Rat
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
  • 抗原表位
    • AA 1-250
  • 标记
    • His tag
    • His tag,GST tag
    • Myc-DYKDDDDK Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
  • Supplier
    • antibodies-online
    • OriGene

Aliases for PLCE1 蛋白

phospholipase C, epsilon 1 (PLCE1) 蛋白
phospholipase C epsilon 1 (PLCE1) 蛋白
phospholipase C, epsilon 1 (plce1) 蛋白
phospholipase C epsilon 1 (plce1) 蛋白
phospholipase C, epsilon 1 (Plce1) 蛋白
4933403A21Rik 蛋白
mKIAA1516 蛋白
NPHS3 蛋白
PLCE 蛋白
Plce 蛋白
PLCE1 蛋白
PLCepsilon 蛋白
PPLC 蛋白
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