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PLAU 抗体

(Plasminogen Activator, Urokinase (PLAU))
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].

Active filters:

  • 抗原: PLAU
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6846488
Recombinant PLAU 抗体 (Alexa Fluor 647) PLAU · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN7679392
Recombinant PLAU 抗体 PLAU · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • WB (Western Blotting: 所列应用)
  • 100 μL
  • 30 μL
  • 50 μL
  • 200 μL
发货至: 中国
ABIN7846133
PLAU 抗体 PLAU · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • 200 μL
发货至: 中国
ABIN7881959
PLAU 抗体 PLAU · Primary Antibody 人 兔 Monoclonal 克隆位点 AABC-16
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN640334
PLAU 抗体 PLAU · Primary Antibody 人 兔
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 1 mg
发货至: 中国
ABIN6336502
PLAU 抗体 PLAU · Primary Antibody Pig 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN6336498
PLAU 抗体 PLAU · Primary Antibody 大鼠 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN2905150
PLAU 抗体 (AA 21-173) PLAU · Primary Antibody 人, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • 100 μL
  • 20 μL
  • 50 μL
发货至: 中国
ABIN1454064
PLAU 抗体 (AA 190-239) PLAU · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • 100 μL
  • 20 μg
  • 50 μL
发货至: 中国
ABIN264790
PLAU 抗体 PLAU · Primary Antibody 人 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
  • 1 mg
发货至: 中国
Primary Antibody
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 647
蛋白类型
Recombinant Antibody
产品编号 ABIN6846488
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
unconjugated
蛋白类型
Recombinant Antibody
产品编号 ABIN7679392
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN7846133
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人
宿主
兔
克隆形成能力
Monoclonal
克隆
AABC-16
标记
unconjugated
抗体亚型
IgG
产品编号 ABIN7881959
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
适用
人
宿主
兔
标记
unconjugated
产品编号 ABIN640334
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
Pig
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6336502
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
大鼠
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6336498
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
适用
人, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 21-173
产品编号 ABIN2905150
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 190-239
产品编号 ABIN1454064
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • EIA (Enzyme Immunoassay: 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
产品编号 ABIN264790

Latest Publications for our PLAU 抗体

Dreymann, Sabrowski, Danso, Menger: "Aptamer-Based Sandwich Assay Formats for Detection and Discrimination of Human High- and Low-Molecular-Weight uPA for Cancer Prognosis and Diagnosis." in: Cancers, Vol. 14, Issue 21, (2022) (PubMed).

Liu, Zheng, Zhang, Wang, Yang, Bai, Dai: "Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells." in: Neurochemical research, Vol. 41, Issue 10, pp. 2728-2751, (2017) (PubMed).

Huang, Chang, Huang, Huang, Tang, Huang, Kuo, Chen, Cheng: "Urokinase-type plasminogen activator resulting from endometrial carcinogenesis enhances tumor invasion and correlates with poor outcome of endometrial carcinoma patients." in: Scientific reports, Vol. 5, pp. 10680, (2016) (PubMed).

Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).

Lee, Oh, Park, Na, Gil, Yang, Lee, Hong: "Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis." in: The Korean journal of internal medicine, Vol. 29, Issue 2, pp. 176-82, (2014) (PubMed).

Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).

Botkjaer, Deryugina, Dupont, Gårdsvoll, Bekes, Thuesen, Chen, Chen, Ploug, Quigley, Andreasen: "Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism." in: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1532-43, (2012) (PubMed).

Coy, Jiménez-Movilla, García-Vázquez, Mondéjar, Grullón, Romar: "Oocytes use the plasminogen-plasmin system to remove supernumerary spermatozoa." in: Human reproduction (Oxford, England), Vol. 27, Issue 7, pp. 1985-93, (2012) (PubMed).

Kim, Minai-Tehrani, Kim, Shin, Hong, Kim, Lee, Chang, Yu, Bang, Cho, Yoon, Yu, Jiang, Cho: "Suppression of tumor growth in H-ras12V liver cancer mice by delivery of programmed cell death protein 4 using galactosylated poly(ethylene glycol)-chitosan-graft-spermine." in: Biomaterials, Vol. 33, Issue 6, pp. 1894-902, (2011) (PubMed).

Eefting, de Vries, Grimbergen, Karper, van Bockel, Quax et al.: "In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase ..." in: Journal of vascular surgery, Vol. 51, Issue 2, pp. 429-37, (2010) (PubMed).

Aliases for PLAU 抗体

plasminogen activator, urokinase (PLAU) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ002131) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ006543) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ013396) 抗体
urokinase-type plasminogen activator (CpipJ_CPIJ013623) 抗体
plasminogen activator, urokinase (Plau) 抗体
ATF 抗体
BDPLT5 抗体
PLAU 抗体
QPD 抗体
u-PA 抗体
UPA 抗体
uPA 抗体
UPAM 抗体
URK 抗体
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