anti-PIK3CA (PIK3CA) 抗体产品概述

Full name:: anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide 抗体 (PIK3CA)

在www.antibodies-online.cn可供203 Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) 抗体的29不同的供货商。再加上，我们可以发PIK3CA 试剂盒 (10) 和 PIK3CA 蛋白 (4)和数多这个蛋白质的别的产品。总共228 PIK3CA产品已列进来了。

别名:: 6330412C24Rik, C-P3K, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, p110, p110-alpha, p110alpha, pi3-k, PI3-kinase, PI3K, PI3K-alpha

列出全部抗体	基因	基因ID	UniProt
	PIK3CA	18706	P42337
	PIK3CA	5290	P42336
	PIK3CA	170911
显示所有的来源显示所有的同义词

最受欢迎的抗anti-PIK3CA (PIK3CA) 抗体

选择您的来源和应用

抗Mouse (Murine) PIK3CA 抗体:

抗Human PIK3CA 抗体:

抗Rat (Rattus) PIK3CA 抗体:

所有可销售的anti-PIK3CA 抗体

您会转到已过滤好的搜索

显示和anti-PIK3CA 抗体相应的途径

引用最多的anti-PIK3CA 抗体

Human Monoclonal PIK3CA Primary Antibody for ICC, FACS - ABIN969555 : Edwards, Witherspoon, Wang, Afrasiabi, Pham, Birnbaumer, Lipkin: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. in Cancer research 2009 (PubMed)
Show all 3 Pubmed References
Human Polyclonal PIK3CA Primary Antibody for FACS, IHC (p) - ABIN1882113 : Singh, Reddy, Goberdhan, Walsh, Dao, Ngai, Chou, O-Charoenrat, Levine, Rao, Stoffel: p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. in Genes & development 2002 (PubMed)
Show all 3 Pubmed References
Human Polyclonal PIK3CA Primary Antibody for ICC, IF - ABIN4345590 : McCaughan, Pole, Bankier, Konfortov, Carroll, Falzon, Rabbitts, George, Dear, Rabbitts: Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer. in American journal of respiratory and critical care medicine 2010 (PubMed)
Show all 2 Pubmed References
Human Polyclonal PIK3CA Primary Antibody for ELISA, IHC - ABIN188684 : López-Knowles, Hernández, Malats, Kogevinas, Lloreta, Carrato, Tardón, Serra, Real: PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors. in Cancer research 2006 (PubMed)
Show all 2 Pubmed References
Human Polyclonal PIK3CA Primary Antibody for IF (p), IHC (p) - ABIN677198 : Paul-Samojedny, Suchanek, Borkowska, Pude?ko, Owczarek, Kowalczyk, Machnik, Fila-Dani?ow, Kowalski: Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells. in BioMed research international 2014 (PubMed)
Human Polyclonal PIK3CA Primary Antibody for IHC, ELISA - ABIN334459 : Abubaker, Bavi, Al-Haqawi, Jehan, Munkarah, Uddin, Al-Kuraya: PIK3CA alterations in Middle Eastern ovarian cancers. in Molecular cancer 2009 (PubMed)
Show all 2 Pubmed References

更多抗PIK3CA的相互作用对抗体

Mouse (Murine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

High PI3k expression is associated with gastrointestinal stromal tumor.
High PI3K expression is sensitive to initial injury intensity induced by freeze damage.
excessive proliferation of endometrial epithelial cells was observed in Pik3cad/d mice. Our studies suggest that Pik3ca has a critical role in uterine gland development and female fertility
Long latency DMBA induced mouse mammary tumors reproduce the molecular profile of human luminal breast carcinomas, displaying a high incidence of activating Pik3caH1047 and loss of function Pten mutations.
Data show that the phosphoinositide 3-kinase (PI3K) inhibitor BKM120 led to a precipitous drop in DNA synthesis within 8 h of drug treatment, whereas DNA synthesis in normal tissues was less affected.
Using genetic inactivation of the growth and metabolism regulator, Pik3ca (encoding PIK3CA also known as p110alpha, alpha/+), the interplay between the maternal genome and the fetal genome on placental phenotype, was examined.
these results identify the PI3K-GSK3-SMAD1 (显示 SMAD1 抗体) axis as a central node integrating multiple signaling networks that govern bone formation and homeostasis.
Data suggest a critical role for KDM3A (显示 KDM3A 抗体) in the PI3K/AP-1 (显示 JUN 抗体) oncogenic axis and propose a novel strategy for inhibition of KDM3A (显示 KDM3A 抗体) against liver tumor development under PI3K pathway activation.
Data show that tumors lacking PSMA had less than half the abundance of type 1 insulin-like growth factor receptor (IGF-1R), less activity in the survival pathway mediated by PI3K-AKT signaling, and more activity in the proliferative pathway mediated by MAPK-ERK1/2 signaling.
Both PIK3CA mutants H1047R and E545K are able to activate the AKT/mTOR pathway. An intact AKT2/mTOR complex 1 cascade is required for tumourigenesis induced by H1047R/c-Met or E545K/c-Met in the liver in mice.

Human Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

Oncogenic PIK3CA alters methionine and cysteine utilization, partly by inhibiting xCT (显示 SLC7A11 抗体) to contribute to the methionine dependency phenotype in human breast cancer cells.
The bladder cancer cell line TCCSUP, which harbors a PIK3CA E545K mutation, was sensitive to pictilisib compared to cell lines with wild-type PIK3CA Pictilisib exhibited stronger antitumor activity in bladder cancer patient-derived xenografts models with PI3KCA H1047R mutation or amplification than the control patient-derived xenografts model
By monitoring single-cell dynamics in each of these contexts, the authors identified PI3K/Akt (显示 AKT1 抗体) regulation of glycolysis as a multifaceted modulator of single-cell metabolic dynamics that is required to maintain metabolic stability in proliferating cells.
results suggest that c-Jun (显示 JUN 抗体), p38 MAPK (显示 MAPK14 抗体), PIK3CA/Akt (显示 AKT1 抗体), and GSK3 signaling involved in the effect of miR (显示 MLXIP 抗体)-203 on the proliferation of hepatocellular carcinoma cells.
these results suggest that aspirin inhibited human uterine leiomyoma cell growth by regulating KRasp110alpha interaction. Aspirin which targeting on interaction between K-Ras (显示 HRAS 抗体) and p110alpha may serve as a new therapeutic drug for uterine leiomyoma treatment.
PIK3CA mutation is a distinctive genetic feature of NSCLC with COPD (显示 ARCN1 抗体), regardless of age, smoking dose, pathological stage, and histology.
In this study of 71 patients with advanced solid tumors who had received prior treatments (86% of whom were PIK3CA mutated), 3 different dose schedules of TAK (显示 CDK9 抗体)-117 were evaluated. The MTD (显示 MT1E 抗体) of TAK (显示 CDK9 抗体)-117 was established as 150 mg once daily and 900 mg for both intermittent (MWF/MTuW) schedules.
Results show that head and neck squamous cell carcinoma tumors with low P120CTN (显示 CTNND1 抗体) and PI3K pathway mutations have higher levels of MMP1 (显示 MMP1 抗体) compared to tumors with high P120CTN (显示 CTNND1 抗体) and no PI3K pathway mutations demonstrating that P120CTN (显示 CTNND1 抗体) downregulation and PIK3CA mutations promote MMP1 (显示 MMP1 抗体)-driven invasion.
Case Reports: PIK3CA mutations are present in multiple tissues of facial infiltrating lipomatosis.
p85alpha plays a tumor-suppressive role in transformation; p110alpha-selective therapeutics may be effective in the treatment of breast cancer patients with PIK3R1 loss

Cow (Bovine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

There are multiple conformations in equilibrium during the course of PI3K SH3 domain (显示 ITSN1 抗体) unfolding.
PI3K has a role in activation of 5'-AMP (显示 TMPRSS5 抗体)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells
Production of PtdIns3P by PI3K-C2alpha (显示 PIK3C2A 抗体) is required for acquisition of fusion competence in neurosecretion.
crystallographic and biochemical approaches used to gain insight into activating mutations in two noncatalytic p110alpha domains-the adaptor-binding and the helical domains

PIK3CA 抗原简介

Antigen Summary

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

Alternative names and synonyms associated with PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) 抗体
Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (pik3ca) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (Pik3ca) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (Pik3ca) 抗体

6330412C24Rik 抗体
C-P3K 抗体
caPI3K 抗体
CLOVE 抗体
CWS5 抗体
MCAP 抗体
MCM 抗体
MCMTC 抗体
p110 抗体
p110-alpha 抗体
p110alpha 抗体
pi3-k 抗体
PI3-kinase 抗体
PI3K 抗体
PI3K-alpha 抗体

Protein level used designations for PIK3CA

, , , , , , , , , , , , , , , , , , , , phosphoinositide-3-kinase, catalytic, alpha polypeptide Phosphoinositide-3-kinase, catalytic, alpha polypeptide PI3-kinase subunit alpha PI3K-alpha PI3Kalpha phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform phosphoinositide-3-kinase catalytic alpha polypeptide ptdIns-3-kinase subunit alpha ptdIns-3-kinase subunit p110-alpha serine/threonine protein kinase PIK3CA PI3-kinase p110 subunit alpha phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha phosphatidylinositol 3-kinase, catalytic, alpha polypeptide phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform PI3K p110alpha ptdIns-3-kinase p110 phosphoinositide 3-kinase catalytic subunit

GENE ID	SPECIES
460858	Pan troglodytes
5702156	Giardia lamblia ATCC 50803
100144924	Xenopus (Silurana) tropicalis
100229768	Taeniopygia guttata
100337822	Oryctolagus cuniculus
18706	Mus musculus
5290	Homo sapiens
282306	Bos taurus
170911	Rattus norvegicus
488084	Canis lupus familiaris
424971	Gallus gallus

anti-PIK3CA (PIK3CA) 抗体精选生产商

您还需要查找其他产品吗？

电话:	+1 877 302 8632
传真:	+1 888 205 9894 (Toll-free)
电子邮件:	orders@antibodies-online.cn