PIN1 抗体
(Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011].
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Latest Publications for our PIN1 抗体
: "Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP." in: Journal of cellular physiology, Vol. 229, Issue 12, pp. 2166-74, (2014) (PubMed).: "Pin1 plays a critical role as a molecular switch in canonical BMP signaling." in: Journal of cellular physiology, Vol. 230, Issue 3, pp. 640-7, (2014) (PubMed).
: "The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor α in breast cancer." in: PLoS ONE, Vol. 8, Issue 2, pp. e55355, (2013) (PubMed).
: "Androgen receptor serine 81 mediates Pin1 interaction and activity." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 18, pp. 3415-20, (2013) (PubMed).
: "Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1." in: Cell death and differentiation, Vol. 19, Issue 7, pp. 1152-61, (2012) (PubMed).
: "Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity." in: Biochimica et biophysica acta, Vol. 1783, Issue 6, pp. 1121-8, (2008) (PubMed).
: "Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity." in: Journal of neurochemistry, Vol. 106, Issue 2, pp. 734-45, (2008) (PubMed).
: "Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy." in: The Journal of clinical investigation, Vol. 118, Issue 5, pp. 1877-89, (2008) (PubMed).
: "The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production." in: Nature, Vol. 440, Issue 7083, pp. 528-34, (2006) (PubMed).
: "Prolyl isomerase Pin1 expression predicts prognosis in patients with esophageal squamous cell carcinoma and correlates with cyclinD1 expression." in: International journal of oncology, Vol. 29, Issue 2, pp. 329-34, (2006) (PubMed).
Aliases for PIN1 抗体
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (PIN1) 抗体peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (Pin1) 抗体
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (pin1) 抗体
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog (pin1.S) 抗体
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Pin1) 抗体
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog (pin1.L) 抗体
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (ppiD) 抗体
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PITG_11123) 抗体
peptidyl-prolyl cis-trans isomerase Pin1 (pin1) 抗体
peptidyl-prolyl cis-trans isomerase Pin1 (LOC103419188) 抗体
0610025L01Rik 抗体
D9Bwg1161e 抗体
DOD 抗体
dod 抗体
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pin1 抗体
Pin1 抗体
pin1a 抗体
pin1b 抗体
PPIase pin1 抗体
UBL5 抗体
ubl5 抗体
zgc:73206 抗体
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