(Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008].
Taron, Colussi, Wiedman, Orlean, Taron: "Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36083-92, (2004) (PubMed).
Aliases for PIGZ 抗体
phosphatidylinositol glycan anchor biosynthesis, class Z (Pigz) 抗体 phosphatidylinositol glycan anchor biosynthesis class Z (PIGZ) 抗体 phosphatidylinositol glycan anchor biosynthesis class Z (Pigz) 抗体 F630022B06Rik 抗体 GPI-MT-IV 抗体 PIG-Z 抗体 SMP3 抗体