PIGZ 抗体 (N-Term)
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北京 101111
Quick Overview for PIGZ 抗体 (N-Term) (ABIN2776579)
抗原
See all PIGZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- PIGZ Antibody - N-terminal region
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序列
- VLWGGLSLLR VLWCLLPQTG YVHPDEFFQS PEVMAEDILG VQAARPWEFY
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预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 80%
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产品特性
- This is a rabbit polyclonal antibody against PIGZ. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIGZ
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anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ) (AA 36-85) antibody
PIGZ 适用: 人, Cow, 豚鼠, 马, 兔, Bat, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ) (AA 1-130) antibodyPIGZ 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41020-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Human Smp3p adds a fourth mannose to yeast and human glycosylphosphatidylinositol precursors in vivo." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 36083-92, (2004) (PubMed).
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- PIGZ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Z (PIGZ))
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别名
- PIGZ
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背景
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Background Information: The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.
Gene Name: Phosphatidylinositol glycan anchor biosynthesis, class Z
Alternative Symbols: SMP3, PIG-Z, GPI-MT-IV
Protein Name: GPI mannosyltransferase 4
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分子量
- 63kDa
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基因ID
- 80235
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NCBI登录号
- NP_079439
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UniProt
- Q86VD9
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途径
- Inositol Metabolic Process
抗原
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