PIAS4 抗体
(Protein Inhibitor of Activated STAT, 4 (PIAS4))
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
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58 results :
PIAS4
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC, IF, ICC
宿主: 兔
Polyclonal
unconjugated
PIAS4
适用: 人
WB, IHC (p)
宿主: 兔
Polyclonal
RB0680
unconjugated
2 references
PIAS4
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Bat, 小鸡, Pig, Hamster, 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
1 image
PIAS4
适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼
WB
宿主: 兔
Polyclonal
unconjugated
1 image
1 reference
Latest Publications for our PIAS4 抗体
: "SUMOylation proteins in breast cancer." in: Breast cancer research and treatment, Vol. 144, Issue 3, pp. 519-30, (2014) (PubMed).: "Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage." in: Journal of cell science, Vol. 126, Issue Pt 22, pp. 5284-92, (2013) (PubMed).
: "DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): a prospective randomized, controlled trial." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 20, pp. 6438-45, (2009) (PubMed).
: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).
: "MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 11, pp. 2725-37, (2007) (PubMed).
: "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through ..." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25850-66, (2006) (PubMed).
: "The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis." in: Molecular cell, Vol. 22, Issue 6, pp. 783-94, (2006) (PubMed).
: "SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3506-18, (2005) (PubMed).
: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).
: "Convergence of interferon-gamma and progesterone signaling pathways in human endometrium: role of PIASy (protein inhibitor of activated signal transducer and activator of transcription-y)." in: Molecular endocrinology (Baltimore, Md.), Vol. 18, Issue 8, pp. 1988-99, (2004) (PubMed).
Aliases for PIAS4 抗体
protein inhibitor of activated STAT 4 (PIAS4) 抗体protein inhibitor of activated STAT, 4 (Pias4) 抗体
protein inhibitor of activated STAT, 4a (pias4a) 抗体
protein inhibitor of activated STAT 4 L homeolog (pias4.L) 抗体
protein inhibitor of activated STAT 4 (pias4) 抗体
protein inhibitor of activated STAT 4 (Pias4) 抗体
protein inhibitor of activated STAT, 4b (pias4b) 抗体
LOC100219439 抗体
Pias-gamma 抗体
pias4 抗体
pias4l 抗体
Piasg 抗体
piasg 抗体
PIASY 抗体
piasy 抗体
wu:fc54c11 抗体
wu:fi18c10 抗体
wu:fi20e09 抗体
wu:fi26h11 抗体
wu:fk93f11 抗体
zgc:63923 抗体
zgc:66410 抗体
ZMIZ6 抗体
zmiz6 抗体
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