Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 抗体
(Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
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Latest Publications for our Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 抗体
: "The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma." in: Molecular cancer, Vol. 17, Issue 1, pp. 93, (2018) (PubMed).: "Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ..." in: Endocrinology, Vol. 145, Issue 6, pp. 2845-57, (2004) (PubMed).
: "The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation." in: Biochemical and biophysical research communications, Vol. 316, Issue 4, pp. 1022-8, (2004) (PubMed).
: "Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells." in: Oncogene, Vol. 22, Issue 3, pp. 392-400, (2003) (PubMed).
: "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." in: Journal of virology, Vol. 77, Issue 4, pp. 2539-49, (2003) (PubMed).
: "Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation." in: Molecular pharmacology, Vol. 63, Issue 3, pp. 639-45, (2003) (PubMed).
: "Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45." in: Journal of cancer research and clinical oncology, Vol. 130, Issue 1, pp. 8-14, (2003) (PubMed).
Aliases for Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG) 抗体phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (Pik3cg) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (pik3cg) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (pik3cg) 抗体
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (Pik3cg) 抗体
si:rp71-17i16.5 (si:rp71-17i16.5) 抗体
5830428L06Rik 抗体
p110gamma 抗体
p120-PI3K 抗体
PI3CG 抗体
PI3K 抗体
Pi3k 抗体
pi3k 抗体
PI3Kgamma 抗体
PIK3 抗体
wu:fb15d07 抗体
zgc:77033 抗体
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