PGC 蛋白
(Pepsinogen C (PGC))
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].
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26 results
PGC
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
PGC
宿主: 人
宿主: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
PGC
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by reducing SDS-PAGE.
PGC
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
PGC
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Aliases for PGC 蛋白
progastricsin (pepsinogen C) (PGC) 蛋白progastricsin (PGC) 蛋白
progastricsin (pepsinogen C) (Pgc) 蛋白
progastricsin (Pgc) 蛋白
2210410L06Rik 蛋白
CPGC 蛋白
gastricsin 蛋白
Gastricsin 蛋白
PEPC 蛋白
Pg-1 蛋白
PG1 蛋白
PGC 蛋白
PGII 蛋白
PGNC 蛋白
Upg-1 蛋白
Upg1 蛋白
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