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Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide

UCP1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985889
发货至: 中国

Quick Overview for Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1) (N-Term) Peptide (ABIN985889)

抗原

UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

宿主

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    序列

    GLPAGLQRQI SSASLRIGLY DTVQEFLTAG KETAPSLGSK ILAGLTTGGV

    产品特性

    This is a synthetic peptide designed for use in combination with anti-UCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

    背景

    Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

    Alias Symbols: SLC25A7, UCP

    Protein Interaction Partner: CIDEA,TOMM20,TOMM20

    Protein Size: 307

    分子量

    34 kDa

    基因ID

    7350

    NCBI登录号

    NM_021833, NP_068605

    UniProt

    P25874
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