This is a synthetic peptide designed for use in combination with anti-UCP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
UCP1
(Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
别名
ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 Peptide, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 Peptide, ATPUMP1 Peptide, ATUCP1 Peptide, UCP Peptide, UCP1 Peptide, UNCOUPLING PROTEIN 1 Peptide, plant uncoupling mitochondrial protein 1 Peptide, ucp Peptide, slc25a7 Peptide, SLC25A7 Peptide, AI385626 Peptide, Slc25a7 Peptide, Ucp Peptide, Ucpa Peptide, Uncp Peptide, plant uncoupling mitochondrial protein 1 Peptide, uncoupling protein 1 Peptide, uncoupling protein 1 L homeolog Peptide, uncoupling protein 1 (mitochondrial, proton carrier) Peptide, PUMP1 Peptide, UCP1 Peptide, ucp1.L Peptide, ucp1 Peptide, Ucp1 Peptide
背景
Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.