Thioredoxin Interacting Protein (TXNIP) (Middle Region) Peptide
TXNIP
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN985780
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Thioredoxin Interacting Protein (TXNIP) (Middle Region) Peptide (ABIN985780)
抗原
TXNIP
(Thioredoxin Interacting Protein (TXNIP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEKKVSC
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TXNIP Antibody(ARP59054_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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背景
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TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Alias Symbols: EST01027, HHCPA78, THIF, VDUP1
Protein Interaction Partner: KPNA2,TXN,HDAC1,KPNA2,SCEL,SMURF2,TXN,TXNRD1,ZBTB16,ZBTB32,HDAC1,SCEL,TXN,ZBTB16,ZBTB32
Protein Size: 391 -
分子量
- 44 kDa
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基因ID
- 10628
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NCBI登录号
- NM_006472, NP_006463
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UniProt
- Q9H3M7
抗原
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