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Thioredoxin Interacting Protein (TXNIP) Peptide

TXNIP 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN937587
发货至: 中国
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Quick Overview for Thioredoxin Interacting Protein (TXNIP) Peptide (ABIN937587)

抗原

TXNIP (Thioredoxin Interacting Protein (TXNIP))

宿主

哺乳动物

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
    Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    TXNIP (Thioredoxin Interacting Protein (TXNIP))

    背景

    TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.

    分子量

    44 kDa
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