Thioredoxin Interacting Protein (TXNIP) Peptide
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北京 101111
Quick Overview for Thioredoxin Interacting Protein (TXNIP) Peptide (ABIN937587)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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背景
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
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分子量
- 44 kDa
抗原
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