Transferrin Receptor (p90, CD71) (TFRC) (N-Term) Peptide
TFRC
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all Transferrin Receptor (TFRC) products
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GYLGYCKGVE PKTECERLAG TESPVREEPG EDFPAARRLY WDDLKRKLSE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TFRC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 背景
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TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Alias Symbols: CD71, TFR, TFR1, TRFR, T9, TR, p90
Protein Interaction Partner: ACAP1,TF,ACAP1,CD247,CD4,GABARAP,HFE,RAB5B,RANBP9,TF,TFRC,AI837181,AT5G46630,BST2,GABARAP,HDAC5,HFE,PXK,RYK,SVIP,TF,TFRC,nef
Protein Size: 760 - 分子量
- 84 kDa
- 基因ID
- 7037
- NCBI登录号
- NM_003234, NP_003225
- UniProt
- P02786
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